Friday, April 12, 2013 - 8:45am to 9:45am
KEC 1007

Speaker Information

Li-Jing Larry Cheng
Research Assistant Professor
Department of Chemical and Biomolecular Engineering
University of Notre Dame

Abstract

Ions in nanofluidic devices or ion conductive materials behave in a similar way to electrons in semiconducting materials. This resemblance inspired us to develop ion conductive devices to mimic the functions of semiconductor counterparts which further led to new ways of manipulating ions and molecules with electrical control and detecting biomolecules via ionic signals. With integration to microfluidic devices, these ion conductive devices can be specifically designed to create a family of function, such as biosensing, microfluidic pH tuning, molecular preconcentration and separation which serve as basic components for lab-on-a-chip devices and diagnosis platforms. Several applications based on these technologies will be presented in this talk, including a microfluidic biosensing platform enabling multi-target, rapid and sensitive detection of nucleic acid suitable for portable point-of-care diagnostic devices. Another example is a high-throughput microfluidic protein separation platform that would foster proteomics technology for biomarker discovery. Based on the current development in nanoporous materials and microfluidics, this talk will also sketch how the nanomaterials and novel device design could advance technologies for medical diagnostics and future electronics.

Speaker Bio

Dr. Li-Jing Larry Cheng received his B.S. and M.S. in Electronics Engineering form National Chiao Tung University in Taiwan (1998, 2000) and Ph.D. in Electrical Engineering in 2008 from the University of Michigan Ann Arbor. His graduate research focused on the development of biomolecular motor-based devices and the study of electrokinetics in nanofluidics. He joined University of Notre Dame since 2010 as a Research Assistant Professor in the Advanced Diagnostics and Therapeutics Initiative and the Department of Chemical & Biomolecular Engineering. His current research aims to develop novel biosensing devices for virus and pathogens detection and microfluidic platforms in the applications of high-throughput cell/ molecular separation and early diagnosis of cancer.