Computational analysis of noncoding RNAs

TitleComputational analysis of noncoding RNAs
Publication TypeJournal Article
Year of Publication2012
AuthorsWashietl, S., S. Will, D. Hendrix, L. A. Goff, J. L. Rinn, B. Berger, and M. Kellis
JournalWiley Interdisciplinary Reviews: RNA
Volume3
Issue6
Pagination759 - 778
Date Published11/2012
Abstract

Noncoding RNAs have emerged as important key players in the cell. Understanding their surprisingly diverse range of functions is challenging for experimental and computational biology. Here, we review computational methods to analyze noncoding RNAs. The topics covered include basic and advanced techniques to predict RNA structures, annotation of noncoding RNAs in genomic data, mining RNA-seq data for novel transcripts and prediction of transcript structures, computational aspects of microRNAs, and database resources.

DOI10.1002/wrna.1134
Short TitleWIREs RNA